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While it has been reported that
2019-05-17
While it has been reported that the combination therapy of As2O3 and ATRA is highly effective not only as the front-line treatment [6], but also in relapsed and treatment-refractory APL patients [7], showing fewer adverse events than the combination of ATRA and chemotherapeutic drugs, the efficacy a
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Introduction Implantable cardioverter defibrillators ICD car
2019-05-17
Introduction Implantable cardioverter-defibrillators (ICD), cardiac resynchronization therapy defibrillators (CRT-D), and cardiac resynchronization therapy (CRT-P) are useful tools for improving the prognosis and/or sudden cardiac death event rate in patients with heart failure and/or fatal ventric
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br Sensors for HF monitoring can be
2019-05-17
Sensors for HF monitoring can be classified according to the technical instrumentation. Table 2 summarizes the sensors that have been used or proposed to monitor the events of HF. The paced QRS enables the determination of the QT duration. In addition, the QRS width, measured as the ventricular de
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Numerous animal studies have demonstrated beyond doubt that
2019-05-17
Numerous animal studies have demonstrated beyond doubt that effective inhibition of osteoclastogenesis or osteoclast function significantly reduces metastatic tumour growth in bone [13–20]. Likewise, clinical trials in patients with non-metastatic or metastatic cancers established that treatment wit
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br Treatment and follow up recommendations
2019-05-17
Treatment and follow-up recommendations for patients receiving aromatase inhibitors Conclusions and future directions It is evident that, in addition to BMD, clinical risk factors can greatly influence fracture risk. In addition to morbidity and mortality, fractures are associated with high he
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ER provides the clinician with a rapid and accurate assessme
2019-05-17
ER-2000® provides the clinician with a rapid and accurate assessment of a patient׳s arrhythmia, improving clinical decision making and clinical outcomes. Further large-scale study is warranted to confirm the accuracy of ER-2000®. Furthermore, the efficacy and usefulness of ER-2000® should be examine
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URMC-099 It is noteworthy that in a recent study Le
2019-05-17
It is noteworthy that in a recent study, Le Scouarnec et al. [199]. estimated the burden of rare coding variation in arrhythmia susceptibility genes among 167 BrS index patients and compared that with 167 individuals ≥65 years old with no history of cardiac arrhythmia. The authors concluded that, ex
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As countries and international platforms engage in post
2019-05-17
As countries and international platforms engage in post-2015 planning, now is the time to envision the ending of preventable maternal deaths, as stressed in a recent manifesto for maternal health. The global health Manumycin A should build on past successes, and accelerate progress towards eliminat
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The two statements from the BRICS partnership
2019-05-17
The two statements from the BRICS partnership could help to inform how best emerging economies can contribute to achievement of ambitious global targets for tuberculosis control. BRICS and other economies in transition have a great responsibility and the potential to contribute to all aspects of car
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Current treatment options for paroxysmal supraventricular ta
2019-05-16
Current treatment options for paroxysmal supraventricular tachycardias include AV buy dhpg blocking agents (verapamil, diltiazem, propranolol, and metoprolol), class IC anti-arrhythmic agents (propafenone and flecainide), and catheter ablation. The identification of frequent coexistence of clinical,
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No es xito peque o que bajo la direcci n
2019-05-16
No es éxito pequeño que “bajo la dirección del maestro Stols” (así indica el colofón del libro) se lograse tal parecido con ellas, pero conviene subrayar que Jusep Torres Campalans no es mera mímesis material de la colección Le goût de notre temps sino también, o ante todo, estructural. El Picasso d
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Las p ginas de este rotativo
2019-05-16
Las páginas de este rotativo pusieron en evidencia las contradicciones y tensiones políticas existentes entre anexionistas e independentistas, La Lucha se mantuvo fiel dpn cost su tendencia de crítica a la ocupación militar estadounidense y proclive a evidenciar los efectos negativos de la administ
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Cambiemos de hemisferio y procedamos a viajar al Cusco del
2019-05-16
Cambiemos de hemisferio y procedamos MM-102 manufacturer viajar al Cusco del siglo xvi. La doctrina o parroquia que es de interés aquí –San Cristóbal Qolqanpata– parece haber sido administrada inicialmente por unos intermediarios apostólicos que poco o nada tuvieron que ver con la orden de San Franc
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Examples of numerically generated vortices and
2019-05-16
Examples of numerically generated vortices and their organizing centers in 3-D excitable media are illustrated in Fig. 1. Panels a to d show 4 different configurations of 3-D scroll waves that were computed using the FitzHugh–Nagumo model [39,40]. Panel a shows an example of the simplest configurati
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ursolic acid Others have observed the marked differences in
2019-05-16
Others have observed the marked differences in clinicopathological characteristics between breast cancer subtypes by IHC study. However, they reported that triple negative and HER2 patients are at high risk of recurrences after adjusting for age, stage and histological grade. Our data support this o
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